P2rx3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

P2rx3
purinergic receptor P2X, ligand-gated ion channel, 3
MGI:1097160

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	ISO	J:155856
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	ISO	J:164563
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	IBA	J:265628
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	IGI	J:97222
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	TAS	J:42467
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0001614	purinergic nucleotide receptor activity	ISO	J:155856
Molecular Function	GO:0001614	purinergic nucleotide receptor activity	ISO	J:164563
Cellular Component	GO:0030424	axon	IDA	J:111371
Cellular Component	GO:0030424	axon	IDA	J:206879
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:119952
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:119952
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:111371
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISS	J:42467
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:119952
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:119952
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0061368	behavioral response to formalin induced pain	ISO	J:155856
Biological Process	GO:0048266	behavioral response to pain	IMP	J:65558
Biological Process	GO:0048266	behavioral response to pain	IMP	J:65557
Biological Process	GO:0048266	behavioral response to pain	IGI	J:112498
Biological Process	GO:0071318	cellular response to ATP	ISO	J:164563
Biological Process	GO:0071318	cellular response to ATP	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:119952
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:65557
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:65558
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:65557
Biological Process	GO:0098662	inorganic cation transmembrane transport	ISO	J:164563
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:119952
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:119952
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:119952
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:119952
Biological Process	GO:0098655	monoatomic cation transmembrane transport	IEA	J:72247
Biological Process	GO:0006812	monoatomic cation transport	IMP	J:65558
Biological Process	GO:0006811	monoatomic ion transport	IMP	J:65557
Biological Process	GO:0006811	monoatomic ion transport	IMP	J:65557
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:105400
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:105400
Biological Process	GO:0019228	neuronal action potential	ISO	J:155856
Biological Process	GO:0030432	peristalsis	IMP	J:105400
Biological Process	GO:0030432	peristalsis	IMP	J:105400
Biological Process	GO:1904058	positive regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0070207	protein homotrimerization	ISO	J:164563
Biological Process	GO:0048167	regulation of synaptic plasticity	IMP	J:119952
Biological Process	GO:0033198	response to ATP	IGI	J:112498
Biological Process	GO:0033198	response to ATP	IMP	J:105400
Biological Process	GO:0033198	response to ATP	IGI	J:112498
Biological Process	GO:0033198	response to ATP	IMP	J:111371
Biological Process	GO:0033198	response to ATP	IMP	J:65558
Biological Process	GO:0033198	response to ATP	IMP	J:65557
Biological Process	GO:0033198	response to ATP	IMP	J:105400
Biological Process	GO:0033198	response to ATP	IGI	J:112498
Biological Process	GO:0033198	response to ATP	IMP	J:119952
Biological Process	GO:0033198	response to ATP	IGI	J:112498
Biological Process	GO:0009743	response to carbohydrate	IMP	J:103231
Biological Process	GO:0009409	response to cold	IMP	J:103789
Biological Process	GO:0009408	response to heat	IMP	J:103789
Biological Process	GO:0001666	response to hypoxia	IMP	J:86890
Biological Process	GO:0009612	response to mechanical stimulus	IMP	J:111371
Biological Process	GO:0010033	response to organic substance	IMP	J:65558
Biological Process	GO:0010033	response to organic substance	IMP	J:65557
Biological Process	GO:0009266	response to temperature stimulus	IMP	J:65558
Biological Process	GO:0050909	sensory perception of taste	IGI	J:103231
Biological Process	GO:0014832	urinary bladder smooth muscle contraction	IMP	J:112498
Biological Process	GO:0014832	urinary bladder smooth muscle contraction	IGI	J:112498
Biological Process	GO:0014832	urinary bladder smooth muscle contraction	IMP	J:65557

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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