GO Annotations Graph

• Symbol: Fap
• Name: fibroblast activation protein
• ID: MGI:109608

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	ISO	J:164563
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	IBA	J:265628
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	ISO	J:73065
Molecular Function	GO:0008233	peptidase activity	IDA	J:48813
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008236	serine-type peptidase activity	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	IDA	J:202837
Cellular Component	GO:0045178	basal part of cell	IDA	J:202837
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	IDA	J:91461
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:1905368	peptidase complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0043542	endothelial cell migration	ISO	J:164563
Biological Process	GO:1902362	melanocyte apoptotic process	IDA	J:91461
Biological Process	GO:0097325	melanocyte proliferation	IDA	J:91461
Biological Process	GO:0060244	negative regulation of cell proliferation involved in contact inhibition	IDA	J:91461
Biological Process	GO:0010716	negative regulation of extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:1903054	negative regulation of extracellular matrix organization	ISO	J:164563
Biological Process	GO:1900119	positive regulation of execution phase of apoptosis	IDA	J:91461
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IBA	J:265628
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:91461
Biological Process	GO:0010710	regulation of collagen catabolic process	ISO	J:164563