GO Annotations Graph

• Symbol: Cfc1
• Name: cryptic, EGF-CFC family member 1
• ID: MGI:109448

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070697	activin receptor binding	IPI	J:183227
Molecular Function	GO:0038100	nodal binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-1181357
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-1225898
Biological Process	GO:0048856	anatomical structure development	IBA	J:265628
Biological Process	GO:0048856	anatomical structure development	IGI	J:70278
Biological Process	GO:0048856	anatomical structure development	IGI	J:70278
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:70278
Biological Process	GO:0060413	atrial septum morphogenesis	IMP	J:58104
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:222159
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:58104
Biological Process	GO:0048546	digestive tract morphogenesis	IMP	J:58104
Biological Process	GO:0007492	endoderm development	IGI	J:70278
Biological Process	GO:0007369	gastrulation	IEA	J:60000
Biological Process	GO:0001947	heart looping	IMP	J:58104
Biological Process	GO:0003007	heart morphogenesis	IMP	J:58104
Biological Process	GO:0060460	left lung morphogenesis	IMP	J:58104
Biological Process	GO:0001889	liver development	IMP	J:58104
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0038092	nodal signaling pathway	IMP	J:183227
Biological Process	GO:0009791	post-embryonic development	IMP	J:58104
Biological Process	GO:0060541	respiratory system development	IMP	J:58104
Biological Process	GO:0048536	spleen development	IMP	J:58104