GO Annotations Graph

• Symbol: Casp7
• Name: caspase 7
• ID: MGI:109383

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	IDA	J:326897
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	IDA	J:93470
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IDA	J:180563
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IDA	J:326897
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IDA	J:326897
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:306586
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:101402
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	ISO	J:164563
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	RCA	J:84168
Molecular Function	GO:0005515	protein binding	IPI	J:180563
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Cellular Component	GO:0008303	caspase complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IDA	J:326897
Cellular Component	GO:0005615	extracellular space	IDA	J:326897
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IBA	J:265628
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0072734	cellular response to staurosporine	ISO	J:164563
Biological Process	GO:0042742	defense response to bacterium	IDA	J:326897
Biological Process	GO:0097194	execution phase of apoptosis	ISO	J:164563
Biological Process	GO:0097194	execution phase of apoptosis	IBA	J:265628
Biological Process	GO:0097194	execution phase of apoptosis	IGI	J:105496
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	NAS	J:320305
Biological Process	GO:0044346	fibroblast apoptotic process	IGI	J:105496
Biological Process	GO:0007507	heart development	IGI	J:105496
Biological Process	GO:0007507	heart development	IGI	J:105496
Biological Process	GO:0006954	inflammatory response	NAS	J:320305
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	NAS	J:320305
Biological Process	GO:0070227	lymphocyte apoptotic process	IMP	J:146876
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0051402	neuron apoptotic process	IDA	J:93470
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1905686	positive regulation of plasma membrane repair	IDA	J:326897
Biological Process	GO:0030163	protein catabolic process	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0051604	protein maturation	ISO	J:164563
Biological Process	GO:0051604	protein maturation	IDA	J:326897
Biological Process	GO:0051604	protein maturation	IDA	J:326897
Biological Process	GO:0016485	protein processing	IDA	J:93470
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	RCA	J:84168
Biological Process	GO:0009411	response to UV	IGI	J:105496