GO Annotations Graph

• Symbol: Enah
• Name: ENAH actin regulator
• ID: MGI:108360

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0005522	profilin binding	IDA	J:53259
Molecular Function	GO:0005522	profilin binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:196124
Molecular Function	GO:0005515	protein binding	IPI	J:247397
Molecular Function	GO:0005515	protein binding	IPI	J:44192
Molecular Function	GO:0005515	protein binding	IPI	J:83872
Molecular Function	GO:0005515	protein binding	IPI	J:91137
Molecular Function	GO:0005515	protein binding	IPI	J:44866
Molecular Function	GO:0005515	protein binding	IPI	J:44192
Molecular Function	GO:0017124	SH3 domain binding	IBA	J:265628
Molecular Function	GO:0017124	SH3 domain binding	IDA	J:51726
Molecular Function	GO:0050699	WW domain binding	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	TAS	J:53259
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-430200
Cellular Component	GO:0030175	filopodium	IDA	J:53259
Cellular Component	GO:0030175	filopodium	IDA	J:91137
Cellular Component	GO:0005925	focal adhesion	IDA	J:44192
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IDA	J:91137
Cellular Component	GO:0030027	lamellipodium	IDA	J:83872
Cellular Component	GO:0043005	neuron projection	IDA	J:53259
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	IDA	J:44192
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:92632
Biological Process	GO:0007015	actin filament organization	IDA	J:44192
Biological Process	GO:0008154	actin polymerization or depolymerization	IBA	J:265628
Biological Process	GO:0008154	actin polymerization or depolymerization	IDA	J:44192
Biological Process	GO:0070358	actin polymerization-dependent cell motility	IDA	J:44192
Biological Process	GO:0070358	actin polymerization-dependent cell motility	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IMP	J:53259
Biological Process	GO:0007411	axon guidance	IGI	J:92632
Biological Process	GO:0007411	axon guidance	IMP	J:92632
Biological Process	GO:0007411	axon guidance	IGI	J:92632
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0001843	neural tube closure	IGI	J:92632
Biological Process	GO:0001843	neural tube closure	IGI	J:53259