GO Annotations Graph

• Symbol: Prkg1
• Name: protein kinase, cGMP-dependent, type I
• ID: MGI:108174

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005246	calcium channel regulator activity	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0030553	cGMP binding	IDA	J:64915
Molecular Function	GO:0004692	cGMP-dependent protein kinase activity	IDA	J:64915
Molecular Function	GO:0004692	cGMP-dependent protein kinase activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:134634
Molecular Function	GO:0005515	protein binding	IPI	J:200390
Molecular Function	GO:0005515	protein binding	IPI	J:64915
Molecular Function	GO:0005515	protein binding	IPI	J:94387
Molecular Function	GO:0004672	protein kinase activity	IDA	J:64915
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IDA	J:93130
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:64915
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IMP	J:146192
Cellular Component	GO:0005886	plasma membrane	IDA	J:180467
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0019934	cGMP-mediated signaling	IMP	J:94387
Biological Process	GO:0019934	cGMP-mediated signaling	IMP	J:94387
Biological Process	GO:0048668	collateral sprouting	IMP	J:135081
Biological Process	GO:0016358	dendrite development	IMP	J:102943
Biological Process	GO:0030900	forebrain development	IMP	J:102943
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0090331	negative regulation of platelet aggregation	ISO	J:164563
Biological Process	GO:0045986	negative regulation of smooth muscle contraction	IMP	J:94387
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	ISO	J:164563
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0001764	neuron migration	IMP	J:102943
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0006468	protein phosphorylation	IDA	J:64915
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0060087	relaxation of vascular associated smooth muscle	IMP	J:94387
Biological Process	GO:0007165	signal transduction	IDA	J:64915