GO Annotations Graph

• Symbol: Bcar1
• Name: breast cancer anti-estrogen resistance 1
• ID: MGI:108091

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:200325
Molecular Function	GO:0005515	protein binding	IPI	J:36262
Molecular Function	GO:0005515	protein binding	IPI	J:61551
Molecular Function	GO:0005515	protein binding	IPI	J:90046
Molecular Function	GO:0005515	protein binding	IPI	J:138258
Molecular Function	GO:0005515	protein binding	IPI	J:200290
Molecular Function	GO:0005515	protein binding	IPI	J:200352
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	IEA	J:60000
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:75087
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5218834
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5218849
Cellular Component	GO:0005925	focal adhesion	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	IDA	J:98248
Cellular Component	GO:0030027	lamellipodium	IDA	J:98248
Cellular Component	GO:0016020	membrane	IMP	J:188792
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0001726	ruffle	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0007015	actin filament organization	ISO	J:164563
Biological Process	GO:0090527	actin filament reorganization	IBA	J:265628
Biological Process	GO:0050851	antigen receptor-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0050853	B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0016477	cell migration	ISO	J:155856
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0016477	cell migration	IDA	J:98248
Biological Process	GO:1990859	cellular response to endothelin	ISO	J:155856
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	ISO	J:164563
Biological Process	GO:0071732	cellular response to nitric oxide	ISO	J:155856
Biological Process	GO:0086100	endothelin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:113670
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0008286	insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007229	integrin-mediated signaling pathway	ISO	J:164563
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	ISO	J:155856
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	ISO	J:155856
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	IDA	J:113670
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	ISO	J:164563