GO Annotations Graph

• Symbol: Adm
• Name: adrenomedullin
• ID: MGI:108058

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031700	adrenomedullin receptor binding	ISO	J:164563
Molecular Function	GO:0031700	adrenomedullin receptor binding	ISO	J:155856
Molecular Function	GO:0031700	adrenomedullin receptor binding	IBA	J:265628
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0005179	hormone activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	ISO	J:164563
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0097647	amylin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0008209	androgen metabolic process	ISO	J:155856
Biological Process	GO:0019731	antibacterial humoral response	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0060670	branching involved in labyrinthine layer morphogenesis	IMP	J:114553
Biological Process	GO:0055074	calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0008283	cell population proliferation	IMP	J:106927
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0048589	developmental growth	IMP	J:114553
Biological Process	GO:0002031	G protein-coupled receptor internalization	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:130931
Biological Process	GO:0007507	heart development	IMP	J:106927
Biological Process	GO:0007507	heart development	IMP	J:114553
Biological Process	GO:0046879	hormone secretion	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0043116	negative regulation of vascular permeability	IMP	J:130931
Biological Process	GO:0045906	negative regulation of vasoconstriction	ISO	J:164563
Biological Process	GO:0001843	neural tube closure	IMP	J:114553
Biological Process	GO:0031102	neuron projection regeneration	ISO	J:155856
Biological Process	GO:0045766	positive regulation of angiogenesis	IMP	J:130931
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:106927
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0010460	positive regulation of heart rate	ISO	J:155856
Biological Process	GO:0010460	positive regulation of heart rate	ISO	J:164563
Biological Process	GO:0010460	positive regulation of heart rate	IBA	J:265628
Biological Process	GO:2001214	positive regulation of vasculogenesis	IMP	J:130931
Biological Process	GO:0031623	receptor internalization	ISO	J:164563
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	ISO	J:164563
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	IBA	J:265628
Biological Process	GO:0002026	regulation of the force of heart contraction	ISO	J:155856
Biological Process	GO:0035809	regulation of urine volume	ISO	J:164563
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:155856
Biological Process	GO:0009611	response to wounding	ISO	J:155856
Biological Process	GO:0060712	spongiotrophoblast layer development	IMP	J:114553
Biological Process	GO:0097084	vascular associated smooth muscle cell development	IMP	J:130931
Biological Process	GO:0001570	vasculogenesis	ISO	J:164563