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GO Annotations Graph
Symbol
Name
ID
Casp3
caspase 3
MGI:107739

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0004190aspartic-type endopeptidase activityIDAJ:93470
Molecular FunctionGO:0004190aspartic-type endopeptidase activityIDAJ:199098
Molecular FunctionGO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activityIMPJ:85809
Molecular FunctionGO:0004197cysteine-type endopeptidase activityIDAJ:180563
Molecular FunctionGO:0004197cysteine-type endopeptidase activityIDAJ:87073
Molecular FunctionGO:0004197cysteine-type endopeptidase activityISOJ:164563
Molecular FunctionGO:0004197cysteine-type endopeptidase activityIDAJ:93322
Molecular FunctionGO:0097153cysteine-type endopeptidase activity involved in apoptotic processIDAJ:206879
Molecular FunctionGO:0097153cysteine-type endopeptidase activity involved in apoptotic processISOJ:164563
Molecular FunctionGO:0097153cysteine-type endopeptidase activity involved in apoptotic processIDAJ:101402
Molecular FunctionGO:0097200cysteine-type endopeptidase activity involved in execution phase of apoptosisIDAJ:79113
Molecular FunctionGO:0097200cysteine-type endopeptidase activity involved in execution phase of apoptosisISOJ:164563
Molecular FunctionGO:0008234cysteine-type peptidase activityIDAJ:124808
Molecular FunctionGO:0008234cysteine-type peptidase activityISOJ:155856
Molecular FunctionGO:0005123death receptor bindingISOJ:155856
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0008233peptidase activityIMPJ:85809
Molecular FunctionGO:0008233peptidase activityIDAJ:87334
Molecular FunctionGO:0008233peptidase activityRCAJ:84168
Molecular FunctionGO:0008233peptidase activityIDAJ:109212
Molecular FunctionGO:0008233peptidase activityISOJ:73065
Molecular FunctionGO:0008233peptidase activityIDAJ:85814
Molecular FunctionGO:0008233peptidase activityIDAJ:85343
Molecular FunctionGO:0008233peptidase activityIMPJ:105496
Molecular FunctionGO:0008233peptidase activityIMPJ:71535
Molecular FunctionGO:0016005phospholipase A2 activator activityISOJ:155856
Molecular FunctionGO:0002020protease bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:180563
Molecular FunctionGO:0005515protein bindingIPIJ:200423
Molecular FunctionGO:0005515protein bindingIPIJ:136306
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:81904
Cellular ComponentGO:0005737cytoplasmIDAJ:220106
Cellular ComponentGO:0005737cytoplasmIDAJ:204287
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0031264death-inducing signaling complexISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:181629
Cellular ComponentGO:0005634nucleusISOJ:164563
Biological ProcessGO:0006915apoptotic processIDAJ:84272
Biological ProcessGO:0006915apoptotic processISOJ:164563
Biological ProcessGO:0006915apoptotic processIMPJ:105496
Biological ProcessGO:0006915apoptotic processISOJ:155856
Biological ProcessGO:0006915apoptotic processIMPJ:85809
Biological ProcessGO:0006915apoptotic processIDAJ:130045
Biological ProcessGO:0006915apoptotic processIMPJ:74972
Biological ProcessGO:0001782B cell homeostasisIMPJ:85809
Biological ProcessGO:0045165cell fate commitmentIMPJ:90057
Biological ProcessGO:0006974cellular response to DNA damage stimulusIDAJ:115386
Biological ProcessGO:0071310cellular response to organic substanceIDAJ:83575
Biological ProcessGO:0030218erythrocyte differentiationIBAJ:161428
Biological ProcessGO:0030218erythrocyte differentiationISOJ:164563
Biological ProcessGO:0097194execution phase of apoptosisISOJ:164563
Biological ProcessGO:0097194execution phase of apoptosisIDAJ:93322
Biological ProcessGO:0097194execution phase of apoptosisIDAJ:79113
Biological ProcessGO:0097194execution phase of apoptosisIMPJ:71535
Biological ProcessGO:0097194execution phase of apoptosisIDAJ:85343
Biological ProcessGO:0097194execution phase of apoptosisIGIJ:105496
Biological ProcessGO:0034349glial cell apoptotic processIMPJ:71535
Biological ProcessGO:0007507heart developmentIGIJ:105496
Biological ProcessGO:0035556intracellular signal transductionISOJ:155856
Biological ProcessGO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressNASJ:220516
Biological ProcessGO:0030216keratinocyte differentiationIMPJ:90057
Biological ProcessGO:0007611learning or memoryISOJ:155856
Biological ProcessGO:0046007negative regulation of activated T cell proliferationIMPJ:85809
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:73065
Biological ProcessGO:0030889negative regulation of B cell proliferationIMPJ:85809
Biological ProcessGO:0045786negative regulation of cell cycleIMPJ:85809
Biological ProcessGO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activityIMPJ:85809
Biological ProcessGO:0051402neuron apoptotic processIMPJ:59317
Biological ProcessGO:0051402neuron apoptotic processIDAJ:93470
Biological ProcessGO:0051402neuron apoptotic processIDAJ:109212
Biological ProcessGO:0051402neuron apoptotic processIMPJ:57545
Biological ProcessGO:0051402neuron apoptotic processIGIJ:59317
Biological ProcessGO:0051402neuron apoptotic processIMPJ:71535
Biological ProcessGO:0030182neuron differentiationIBAJ:161428
Biological ProcessGO:0048011neurotrophin TRK receptor signaling pathwayISOJ:201759
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:155856
Biological ProcessGO:0043085positive regulation of catalytic activityISOJ:155856
Biological ProcessGO:0043525positive regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0016485protein processingIDAJ:93470
Biological ProcessGO:0006508proteolysisRCAJ:84168
Biological ProcessGO:0006508proteolysisISOJ:164563
Biological ProcessGO:0006508proteolysisISOJ:155856
Biological ProcessGO:0009749response to glucoseISOJ:155856
Biological ProcessGO:0042542response to hydrogen peroxideISOJ:155856
Biological ProcessGO:0010033response to organic substanceIDAJ:146128
Biological ProcessGO:0009411response to UVIGIJ:105496
Biological ProcessGO:0009411response to UVIDAJ:115386
Biological ProcessGO:0009611response to woundingIDAJ:85750
Biological ProcessGO:0007605sensory perception of soundIMPJ:69809
Biological ProcessGO:0043029T cell homeostasisIMPJ:85809


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/21/2020
MGI 6.14
The Jackson Laboratory