GO Annotations Graph

• Symbol: Lyst
• Name: lysosomal trafficking regulator
• ID: MGI:107448

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:44170
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	IMP	J:7327
Biological Process	GO:0042742	defense response to bacterium	IMP	J:5405
Biological Process	GO:0042742	defense response to bacterium	IMP	J:20488
Biological Process	GO:0042742	defense response to bacterium	IMP	J:5471
Biological Process	GO:0042832	defense response to protozoan	IMP	J:6946
Biological Process	GO:0051607	defense response to virus	IMP	J:6646
Biological Process	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0071621	granulocyte chemotaxis	IMP	J:5405
Biological Process	GO:0007040	lysosome organization	IMP	J:5338
Biological Process	GO:0007040	lysosome organization	IMP	J:44170
Biological Process	GO:0007040	lysosome organization	IMP	J:6629
Biological Process	GO:0007040	lysosome organization	IMP	J:5514
Biological Process	GO:0007040	lysosome organization	IMP	J:44170
Biological Process	GO:0007040	lysosome organization	IMP	J:7980
Biological Process	GO:0033364	mast cell secretory granule organization	IMP	J:5935
Biological Process	GO:0032438	melanosome organization	IMP	J:5346
Biological Process	GO:0032438	melanosome organization	IMP	J:106442
Biological Process	GO:0032438	melanosome organization	IMP	J:106442
Biological Process	GO:0032438	melanosome organization	IMP	J:106442
Biological Process	GO:0032438	melanosome organization	IMP	J:106442
Biological Process	GO:0032438	melanosome organization	IMP	J:106442
Biological Process	GO:0032438	melanosome organization	IMP	J:5346
Biological Process	GO:0032438	melanosome organization	IMP	J:106442
Biological Process	GO:0007017	microtubule-based process	IMP	J:5728
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	ISO	J:164563
Biological Process	GO:0002446	neutrophil mediated immunity	IMP	J:20488
Biological Process	GO:0006909	phagocytosis	IEA	J:60000
Biological Process	GO:0055091	phospholipid homeostasis	IMP	J:5992
Biological Process	GO:0006644	phospholipid metabolic process	IMP	J:5992
Biological Process	GO:0048753	pigment granule organization	IMP	J:5656
Biological Process	GO:0043473	pigmentation	ISO	J:164563
Biological Process	GO:0043473	pigmentation	ISO	J:155856
Biological Process	GO:0043473	pigmentation	IMP	J:29294
Biological Process	GO:0043473	pigmentation	IMP	J:25388
Biological Process	GO:0043473	pigmentation	IMP	J:7980
Biological Process	GO:0043473	pigmentation	IMP	J:6801
Biological Process	GO:0032816	positive regulation of natural killer cell activation	IMP	J:6801
Biological Process	GO:0008104	protein localization	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:29294
Biological Process	GO:0033299	secretion of lysosomal enzymes	IMP	J:5590
Biological Process	GO:0033299	secretion of lysosomal enzymes	IMP	J:6801
Biological Process	GO:0033299	secretion of lysosomal enzymes	IMP	J:5590
Biological Process	GO:0002456	T cell mediated immunity	IMP	J:6692