Eps8 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Eps8
epidermal growth factor receptor pathway substrate 8
MGI:104684

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:196111
Molecular Function	GO:0003779	actin binding	IDA	J:196125
Molecular Function	GO:0003779	actin binding	IDA	J:161597
Molecular Function	GO:0003779	actin binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:137488
Molecular Function	GO:0005515	protein binding	IPI	J:171832
Molecular Function	GO:0005515	protein binding	IPI	J:150646
Molecular Function	GO:0005515	protein binding	IPI	J:195223
Molecular Function	GO:0005515	protein binding	IPI	J:114805
Molecular Function	GO:0005515	protein binding	IPI	J:196106
Molecular Function	GO:0005515	protein binding	IPI	J:155180
Molecular Function	GO:0005515	protein binding	IPI	J:196111
Molecular Function	GO:0005515	protein binding	IPI	J:196125
Molecular Function	GO:0005515	protein binding	IPI	J:116055
Molecular Function	GO:0005515	protein binding	IPI	J:148808
Molecular Function	GO:0005515	protein binding	IPI	J:116055
Molecular Function	GO:0035591	signaling adaptor activity	IEA	J:72247
Molecular Function	GO:0031267	small GTPase binding	IDA	J:196125
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0005938	cell cortex	IDA	J:196125
Cellular Component	GO:0005938	cell cortex	IDA	J:195223
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:237769
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:237769
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:237769
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:237769
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:237769
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	IDA	J:116055
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:116055
Cellular Component	GO:0032587	ruffle membrane	IDA	J:196125
Cellular Component	GO:0032587	ruffle membrane	IBA	J:265628
Cellular Component	GO:0032420	stereocilium	IDA	J:215946
Cellular Component	GO:0032420	stereocilium	IDA	J:171832
Cellular Component	GO:0032421	stereocilium bundle	IDA	J:200669
Cellular Component	GO:0032426	stereocilium tip	IDA	J:200669
Cellular Component	GO:0045202	synapse	IDA	J:116055
Biological Process	GO:0051764	actin crosslink formation	IMP	J:196106
Biological Process	GO:0051764	actin crosslink formation	IDA	J:161597
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:116055
Biological Process	GO:0051017	actin filament bundle assembly	IMP	J:196106
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:161597
Biological Process	GO:0051017	actin filament bundle assembly	IGI	J:148808
Biological Process	GO:0070358	actin polymerization-dependent cell motility	IDA	J:196111
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:116055
Biological Process	GO:0051016	barbed-end actin filament capping	IDA	J:196111
Biological Process	GO:0051016	barbed-end actin filament capping	IMP	J:195223
Biological Process	GO:0051016	barbed-end actin filament capping	IDA	J:161597
Biological Process	GO:0048149	behavioral response to ethanol	IMP	J:116055
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0036336	dendritic cell migration	IMP	J:176428
Biological Process	GO:0010458	exit from mitosis	IMP	J:195223
Biological Process	GO:1900029	positive regulation of ruffle assembly	IBA	J:265628
Biological Process	GO:0016601	Rac protein signal transduction	IDA	J:196125
Biological Process	GO:0030832	regulation of actin filament length	IMP	J:171832
Biological Process	GO:0008360	regulation of cell shape	IMP	J:195223
Biological Process	GO:0008360	regulation of cell shape	IMP	J:196106
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IEP	J:237769
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:237769
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:237769
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	EXP	J:237769
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:237769
Biological Process	GO:0035023	regulation of Rho protein signal transduction	IBA	J:265628
Biological Process	GO:0007266	Rho protein signal transduction	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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