GO Annotations Graph

• Symbol: Mitf
• Name: melanogenesis associated transcription factor
• ID: MGI:104554

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:96431
Molecular Function	GO:0003677	DNA binding	IDA	J:86229
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:96202
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:79002
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:86229
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	J:191195
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:96431
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0070888	E-box binding	IDA	J:191195
Molecular Function	GO:0005515	protein binding	IPI	J:145836
Molecular Function	GO:0046983	protein dimerization activity	IPI	J:191195
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:96202
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:202853
Molecular Function	GO:0043565	sequence-specific DNA binding	ISA	J:77083
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IC	J:86229
Cellular Component	GO:0005634	nucleus	IDA	J:79002
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0046849	bone remodeling	IMP	J:77083
Biological Process	GO:0043010	camera-type eye development	IGI	J:94374
Biological Process	GO:0030154	cell differentiation	IMP	J:41159
Biological Process	GO:0045165	cell fate commitment	IMP	J:94374
Biological Process	GO:0006351	DNA-templated transcription	ISO	J:155856
Biological Process	GO:1902362	melanocyte apoptotic process	IMP	J:77083
Biological Process	GO:0030318	melanocyte differentiation	IBA	J:265628
Biological Process	GO:0030318	melanocyte differentiation	IMP	J:77083
Biological Process	GO:0030318	melanocyte differentiation	IGI	J:77083
Biological Process	GO:0030318	melanocyte differentiation	IMP	J:29467
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:77083
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:77083
Biological Process	GO:0043473	pigmentation	IGI	J:77083
Biological Process	GO:0043473	pigmentation	IMP	J:77083
Biological Process	GO:0043473	pigmentation	IMP	J:29467
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:86229
Biological Process	GO:2000144	positive regulation of DNA-templated transcription initiation	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:211299
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:180479
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:96202
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96431
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISS	J:77083
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:145836
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	IDA	J:79002
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	IMP	J:77083
Biological Process	GO:0045670	regulation of osteoclast differentiation	IGI	J:89821
Biological Process	GO:0045670	regulation of osteoclast differentiation	IMP	J:89821
Biological Process	GO:2001141	regulation of RNA biosynthetic process	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:191195
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:79002
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:79002