GO Annotations Graph

• Symbol: Atp6v1b1
• Name: ATPase, H+ transporting, lysosomal V1 subunit B1
• ID: MGI:103285

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0015078	proton transmembrane transporter activity	IMP	J:169891
Molecular Function	GO:0015078	proton transmembrane transporter activity	IMP	J:101414
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:169877
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:102456
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:125875
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:102455
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:284463
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:192002
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:148657
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:169891
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:192002
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:101414
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:87491
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:148657
Cellular Component	GO:0005737	cytoplasm	IDA	J:125875
Cellular Component	GO:0005829	cytosol	IDA	J:169891
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:169877
Cellular Component	GO:0016020	membrane	IDA	J:87491
Cellular Component	GO:0016020	membrane	IDA	J:87491
Cellular Component	GO:0005902	microvillus	IDA	J:125875
Cellular Component	GO:0005902	microvillus	IDA	J:169877
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0033180	proton-transporting V-type ATPase, V1 domain	IEA	J:72247
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	ISS	J:87491
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	ISO	J:164563
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	ISO	J:164563
Biological Process	GO:0030534	adult behavior	IMP	J:192002
Biological Process	GO:0046034	ATP metabolic process	IMP	J:204005
Biological Process	GO:0055074	calcium ion homeostasis	ISO	J:164563
Biological Process	GO:0055064	chloride ion homeostasis	IMP	J:204005
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0042048	olfactory behavior	IMP	J:192002
Biological Process	GO:0001503	ossification	ISO	J:164563
Biological Process	GO:0001503	ossification	ISS	J:87491
Biological Process	GO:0045851	pH reduction	ISO	J:164563
Biological Process	GO:0055075	potassium ion homeostasis	IMP	J:204005
Biological Process	GO:0006693	prostaglandin metabolic process	IMP	J:204005
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:1902600	proton transmembrane transport	IMP	J:169891
Biological Process	GO:0010468	regulation of gene expression	IMP	J:193274
Biological Process	GO:0006885	regulation of pH	IMP	J:169891
Biological Process	GO:0006885	regulation of pH	IMP	J:101414
Biological Process	GO:0006885	regulation of pH	ISO	J:73065
Biological Process	GO:0035812	renal sodium excretion	IMP	J:204005
Biological Process	GO:0003096	renal sodium ion transport	IMP	J:204005
Biological Process	GO:0097254	renal tubular secretion	ISO	J:164563
Biological Process	GO:0003091	renal water homeostasis	IMP	J:204005
Biological Process	GO:0007605	sensory perception of sound	ISO	J:87491
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	EXP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IMP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652
Biological Process	GO:0007035	vacuolar acidification	IBA	J:265628
Biological Process	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	ISO	J:164563