GO Annotations Graph

• Symbol: Acod1
• Name: aconitate decarboxylase 1
• ID: MGI:103206

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047613	aconitate decarboxylase activity	IDA	J:325954
Molecular Function	GO:0047613	aconitate decarboxylase activity	IDA	J:196954
Molecular Function	GO:0047613	aconitate decarboxylase activity	ISO	J:164563
Molecular Function	GO:0047613	aconitate decarboxylase activity	IMP	J:279203
Molecular Function	GO:0016829	lyase activity	IEA	J:72247
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:325954
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:196718
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Biological Process	GO:0035458	cellular response to interferon-beta	IDA	J:196718
Biological Process	GO:0071347	cellular response to interleukin-1	IDA	J:196718
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:196955
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:196954
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	IDA	J:196718
Biological Process	GO:0071393	cellular response to progesterone stimulus	IDA	J:196639
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IDA	J:196718
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:196718
Biological Process	GO:0006952	defense response	IDA	J:196954
Biological Process	GO:0006952	defense response	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IMP	J:279203
Biological Process	GO:0007566	embryo implantation	IMP	J:196639
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0050728	negative regulation of inflammatory response	IDA	J:196955
Biological Process	GO:0045824	negative regulation of innate immune response	IDA	J:196955
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	IMP	J:196955
Biological Process	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	IMP	J:196955
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	IDA	J:196955
Biological Process	GO:0032480	negative regulation of type I interferon production	IMP	J:196955
Biological Process	GO:0002760	positive regulation of antimicrobial humoral response	IDA	J:196954
Biological Process	GO:0002760	positive regulation of antimicrobial humoral response	ISO	J:164563
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	IDA	J:196955
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0032496	response to lipopolysaccharide	IDA	J:25077
Biological Process	GO:0072573	tolerance induction to lipopolysaccharide	IDA	J:196955
Biological Process	GO:0072573	tolerance induction to lipopolysaccharide	ISO	J:164563