GO Annotations Graph

• Symbol: Ddx4
• Name: DEAD box helicase 4
• ID: MGI:102670

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IMP	J:243488
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0140693	molecular condensate scaffold activity	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:189932
Molecular Function	GO:0005515	protein binding	IPI	J:243444
Molecular Function	GO:0005515	protein binding	IPI	J:148942
Molecular Function	GO:0005515	protein binding	IPI	J:107318
Molecular Function	GO:0005515	protein binding	IPI	J:152071
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:87812
Molecular Function	GO:0005515	protein binding	IPI	J:117063
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0003724	RNA helicase activity	IBA	J:265628
Cellular Component	GO:0033391	chromatoid body	ISO	J:155856
Cellular Component	GO:0033391	chromatoid body	ISO	J:62087
Cellular Component	GO:0033391	chromatoid body	ISO	J:62087
Cellular Component	GO:0033391	chromatoid body	ISO	J:62087
Cellular Component	GO:0033391	chromatoid body	IDA	J:62087
Cellular Component	GO:0033391	chromatoid body	IDA	J:189647
Cellular Component	GO:0033391	chromatoid body	ISO	J:62087
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:96322
Cellular Component	GO:0005737	cytoplasm	IDA	J:62087
Cellular Component	GO:0005737	cytoplasm	IDA	J:83934
Cellular Component	GO:0005737	cytoplasm	IDA	J:87735
Cellular Component	GO:0005737	cytoplasm	IDA	J:62087
Cellular Component	GO:0005737	cytoplasm	IDA	J:98391
Cellular Component	GO:0005737	cytoplasm	IDA	J:62087
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5605205
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5605213
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5605279
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5605349
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606226
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606252
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5629217
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:83934
Cellular Component	GO:0043186	P granule	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:62087
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:179634
Cellular Component	GO:0071546	pi-body	IDA	J:159518
Cellular Component	GO:0071546	pi-body	IDA	J:155865
Cellular Component	GO:0071546	pi-body	IDA	J:189647
Cellular Component	GO:0071547	piP-body	IDA	J:155865
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:117063
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0043046	DNA methylation involved in gamete generation	IMP	J:159518
Biological Process	GO:0030317	flagellated sperm motility	ISO	J:164563
Biological Process	GO:0007276	gamete generation	IBA	J:265628
Biological Process	GO:0007141	male meiosis I	IMP	J:243488
Biological Process	GO:0007141	male meiosis I	IMP	J:61665
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:159518
Biological Process	GO:0051321	meiotic cell cycle	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010529	negative regulation of transposition	IMP	J:243488
Biological Process	GO:0034587	piRNA processing	IMP	J:243488
Biological Process	GO:0034587	piRNA processing	IMP	J:159518
Biological Process	GO:0032880	regulation of protein localization	IMP	J:117063
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000
Biological Process	GO:0007283	spermatogenesis	IMP	J:159518
Biological Process	GO:0007283	spermatogenesis	IMP	J:243488
Biological Process	GO:0007283	spermatogenesis	IMP	J:61665