GO Annotations Graph

• Symbol: Calcr
• Name: calcitonin receptor
• ID: MGI:101950

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097643	amylin receptor activity	ISO	J:164563
Molecular Function	GO:0097643	amylin receptor activity	ISO	J:164563
Molecular Function	GO:0097643	amylin receptor activity	IBA	J:265628
Molecular Function	GO:0032841	calcitonin binding	ISO	J:155856
Molecular Function	GO:0001635	calcitonin gene-related peptide receptor activity	ISO	J:164563
Molecular Function	GO:0004948	calcitonin receptor activity	ISO	J:155856
Molecular Function	GO:0004948	calcitonin receptor activity	ISO	J:164563
Molecular Function	GO:0004948	calcitonin receptor activity	IBA	J:265628
Molecular Function	GO:0004948	calcitonin receptor activity	IDA	J:22084
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:83111
Cellular Component	GO:0150056	amylin receptor complex 1	ISO	J:164563
Cellular Component	GO:0150057	amylin receptor complex 2	ISO	J:164563
Cellular Component	GO:0150058	amylin receptor complex 3	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0005929	cilium	IDA	J:83111
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:22084
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0097647	amylin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0038041	cross-receptor inhibition within G protein-coupled receptor heterodimer	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0030279	negative regulation of ossification	IMP	J:88964
Biological Process	GO:0001503	ossification	IMP	J:88964
Biological Process	GO:0030316	osteoclast differentiation	IDA	J:29261
Biological Process	GO:0045762	positive regulation of adenylate cyclase activity	ISO	J:164563
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:164563
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IDA	J:49911
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0043488	regulation of mRNA stability	IDA	J:38221
Biological Process	GO:1904645	response to amyloid-beta	ISO	J:164563
Biological Process	GO:0051384	response to glucocorticoid	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:60000