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tk Gene Detail
Summary
  • Symbol
    tk
  • Name
    tail-kinks
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98760
    NCBI Gene: 21874
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 9, Syntenic
  • Mapping Data
    31 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    3 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mutations in this gene result in abnormal vertebrae development, with a shortened and kinked tail especially noticeable.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-15120
References
more
  • Summaries
    All 17
    Phenotypes 4
  • Earliest
    J:14982 Gruneberg H, Genetical studies on the skeleton of the mouse. XVI. Tail-kinks. J Genet. 1955;53:536-50
  • Latest
    J:121463 Kaja S, et al., Redundancy of Cav2.1 channel accessory subunits in transmitter release at the mouse neuromuscular junction. Brain Res. 2007 Apr 27;1143:92-101

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory