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Thy1 Gene Detail
Summary
  • Symbol
    Thy1
  • Name
    thymus cell antigen 1, theta
  • Synonyms
    CD90, T25, theta, Thy-1, Thy1.1, Thy 1.2, Thy-1.2, Thy1.2
  • Feature Type
    protein coding gene
  • IDs
    MGI:98747
    NCBI Gene: 21838
  • Gene Overview
    MyGene.info: THY1
Location & Maps
more
  • Sequence Map
    Chr9:44043384-44048579 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5196 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    THY1, Thy-1 cell surface antigen
  • Vertebrate Orthologs
    9
  • Human Ortholog
    THY1, Thy-1 cell surface antigen
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CD90, CDw90
  • Links
    NCBI Gene ID: 7070
    neXtProt AC: NX_P04216

  • Chr Location
    11q23.3; chr11:119417945-119423536 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    65 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Gene trapped
    1
  • Targeted
    4
  • Incidental Mutations
Homozygous null mice are viable, fertile, and display no abnormalities in the brain and spinal cord, have normal axonal development and regeneration and no behavioral abnormalities. Long term potentiation is inhibited in the dentate gyrus.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016734 VEGA Gene Model | MGI Sequence Detail 5196 C57BL/6J ±  kb
transcript OTTMUST00000040558 VEGA | MGI Sequence Detail 1735 Not Applicable  
polypeptide OTTMUSP00000018127 VEGA | MGI Sequence Detail 162 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    80 from dbSNP Build 142
  • PCR
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 83
    Genomic 18
    cDNA 58
    Primer pair 6
    Other 1

    Microarray probesets 2
Other
Accession IDs
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MGD-MRK-15100, MGD-MRK-15102
References
more
  • Summaries
    All 199
    Developmental Gene Expression 30
    Gene Ontology 15
    Phenotypes 65
  • Earliest
    J:24839 REIF AE, et al., THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES. J Exp Med. 1964 Sep 1;120:413-33
  • Latest
    J:224890 Martinet V, et al., Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells. Nat Commun. 2015;6:7089

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory