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Thy1
Gene Detail
Symbol

Name
ID
Thy1
thymus cell antigen 1, theta
MGI:98747
STS
Synonyms
CD90, T25, theta, Thy-1, Thy1.1, Thy 1.2, Thy-1.2, Thy1.2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(55)
Sequence Map
Chr9:44043384-44048579 bp, + strand
From VEGA annotation of GRCm38

  5196 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4580  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: Thy-1 membrane glycoprotein
Gene Tree: Thy1

Human
homologs
Human Homolog THY1, Thy-1 cell surface antigen
NCBI Gene ID 7070
neXtProt AC  NX_P04216
Human Synonyms  CD90
Human Chr (Location)  11q23.3; chr11:119417945-119423536 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are viable, fertile, and display no abnormalities in the brain and spinal cord, have normal axonal development and regeneration and no behavioral abnormalities. Long term potentiation is inhibited in the dentate gyrus.
 
Interactions
Thy1 interacts with 193 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process angiogenesis, cytoskeleton organization, ...
Component anchored component of external side of plasma membrane, anchored component of membrane, ...
Function enzyme binding, GPI anchor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (28 records)
Data Summary: Results (221)    Tissues (64)    Images (62)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 8
RNA in situ 198
RT-PCR 15
cDNA source data(55)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(83) Genomic(18) cDNA(58) Primer pair(6) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016734 (Evidence)
Ensembl Gene ModelENSMUSG00000032011 (Evidence)
Entrez Gene21838 (Evidence)
UniGene3951
DFCITC1577066, TC1628688, TC1715283
DoTSDT.101337538, DT.533681, DT.94314670
Consensus CDS ProjectCCDS23093.1
International Mouse Knockout Project StatusThy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016734 VEGA Gene Model | MGI Sequence Detail 5196 C57BL/6J ±  kb
transcript OTTMUST00000040558 VEGA | MGI Sequence Detail 1735 Not Applicable 
polypeptide OTTMUSP00000018127 VEGA | MGI Sequence Detail 162 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(2)
Polymorphisms
All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(83 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013151 Immunoglobulin
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003596 Immunoglobulin V-set, subgroup
Protein Ontology PR:000001843 Thy-1 membrane glycoprotein
References
(Earliest) J:24839 REIF AE, et al., THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES. J Exp Med. 1964 Sep 1;120:413-33
(Latest) J:212002 Huang W, et al., ITK tunes IL-4-induced development of innate memory CD8+ T cells in a gammadelta T and invariant NKT cell-independent manner. J Leukoc Biol. 2014 Jul;96(1):55-63
All references(195)
Other
accession IDs
MGD-MRK-15100, MGD-MRK-15102

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory