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sy Gene Detail
Summary
  • Symbol
    sy
  • Name
    shaker-with-syndactylism deletion region
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98457
    NCBI Gene: 20954
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 18, Syntenic
  • Mapping Data
    22 experiments
Human Diseases
more
  • Diseases
    1 with sy mouse models

Human Disease Mouse Models
       Arthrogryposis, Distal, Type 9; DA9   OMIM: 121050
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotypes from 1 allele in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Radiation induced
    1
Mice homozygous for a radiation-induced deletion die within one month of birth exhibiting syndactylous feet and other skeletal malformations, inner ear dysmorphology, deafness, and abnormal behavior characteristic of vestibular dysfunction.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-14674
References
more
  • Summaries
    All 17
    Diseases 1
    Phenotypes 7
  • Earliest
    J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80:220-246
  • Latest
    J:68881 Chaudhry SS, et al., Mutation of the gene encoding fibrillin-2 results in syndactyly in mice. Hum Mol Genet. 2001 Apr 1;10(8):835-43

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory