Rmp1 QTL Detail

Summary

• Symbol
  Rmp1
• Name
  resistance to mousepox
• Synonyms
  Rmp-1

• Feature Type
  QTL
• IDs
  MGI:97934
  NCBI Gene: 104168

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 6, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

This QTL is one of several determining difference in resistance to mortality from infection with ectromelia (mousepox) virus. C57BL/6J is resistant and A/J is susceptible. Resistance is to mortality, rather than to infection per se, as the 50% infectiousdose is similar for all strains.

Sequences &
Gene Models

• NCBI Gene
  104168

Other
Accession IDs

MGD-MRK-13901, MGD-MRK-13904

References

• Summaries
  All 4

  Phenotypes 1
• Earliest
  J:7953 Wallace GD, et al., Genetic determinants of resistance to ectromelia (mousepox) virus-induced mortality. J Virol. 1985 Sep;55(3):890-1
• Latest
  J:28150 Delano ML, et al., Innate resistance to lethal mousepox is genetically linked to the NK gene complex on chromosome 6 and correlates with early restriction of virus replication by cells with an NK phenotype. J Virol. 1995 Sep;69(9):5875-7