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Pygm
Gene Detail
Symbol

Name
ID
Pygm
muscle glycogen phosphorylase
MGI:97830
Synonyms
PG
Feature Type
protein coding gene
Genetic Map
Chromosome 19
4.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr19:6384399-6398459 bp, + strand
From VEGA annotation of GRCm38

  14061 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2145  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PYGM
Protein SuperFamily: glucan phosphorylase
Gene Tree: Pygm

Human
homologs
PYGM, phosphorylase, glycogen, muscle
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5837
neXtProt AC: NX_P11217

Human Chr (Location): 11q12-q13.2; chr11:64746389-64760715 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PYGM

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Pygm interacts with 54 markers (Mir1b, Mir7b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process carbohydrate metabolic process, cellular calcium ion homeostasis, ...
Component cytoplasm, extracellular exosome, ...
Function AMP binding, carbohydrate binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (182)    Tissues (49)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 182
cDNA source data(49)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pygm ; ZFIN pygma, pygmb    NEW 
Molecular
reagents
All nucleic(52) cDNA(51) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000018613 (Evidence)
Ensembl Gene Model ENSMUSG00000032648 (Evidence)
Entrez Gene 19309 (Evidence)
UniGene 27806
DFCI TC1574672
DoTS DT.534027, DT.94369767
NIA Mouse Gene Index U038688
EC 2.4.1.1
Consensus CDS Project CCDS29504.1
International Mouse Phenotyping Consortium Status Pygm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018613 VEGA Gene Model | MGI Sequence Detail 14061 C57BL/6J ±  kb
transcript OTTMUST00000044793 VEGA | MGI Sequence Detail 2874 Not Applicable 
polypeptide OTTMUSP00000020157 VEGA | MGI Sequence Detail 842 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(4) : SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011833 Glycogen/starch/alpha-glucan phosphorylase
InterPro IPR000811 Glycosyl transferase, family 35
Protein Ontology PR:000013522 glycogen phosphorylase, muscle form
References
(Earliest) J:10246 Glaser T, et al., Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively. Genomics. 1989 Oct;5(3):510-21
(Latest) J:221348 de Luna N, et al., Sodium valproate increases the brain isoform of glycogen phosphorylase: looking for a compensation mechanism in McArdle disease using a mouse primary skeletal-muscle culture in vitro. Dis Model Mech. 2015 May 1;8(5):467-72
All references(47)
Other
accession IDs
MGD-MRK-13703, MGI:2147475

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory