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pma Gene Detail
Summary
  • Symbol
    pma
  • Name
    peroneal muscular atrophy
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97628
    NCBI Gene: 18849
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 5, Syntenic
  • Mapping Data
    1 experiment
Human Diseases
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  • Diseases
    2 with pma mouse models

Human Disease Mouse Models
      
IDs
View 1 model
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a spontaneous allele display a club foot and ankle joint immobility at birth, show peroneal muscular atrophy in the hind limbs due to absence of the common peroneal nerve branch, and develop an unusual gait due to a dropped foot in adulthood.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-13368
References
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  • Summaries
    All 9
    Diseases 1
    Phenotypes 7
  • Earliest
    J:6590 Esaki K, et al., [A new mutant in the mouse: peroneal muscular atrophy (author's transl)]. Jikken Dobutsu. 1981 Apr;30(2):151-5
  • Latest
    J:257926 Collinson JM, et al., The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse. Development. 2018 Feb 8;145(3):dev160093

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory