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Pepc Gene Detail
Summary
  • Symbol
    Pepc
  • Name
    peptidase C
  • Synonyms
    Dip-1, Pep3, Pep-3
  • Feature Type
    unclassified gene
  • IDs
    MGI:97541
    NCBI Gene: 109616
  • Alliance
Location &
Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    144 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 5 alleles in 1 genetic background
    5 phenotypes from multigenic genotypes
    62 phenotype references
Electrophoretic variants of red blood cell PEPC are: C57BL/6 has a slow anodal band (a allele); CBA/J and A/He, a faster band (b allele); NZB, ST/b and RIIIS/J, an even faster band (c allele). Heterozygotes have both bands. Mice homozygous for ENU or procarbazine induced null alleles are viable.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-13233, MGD-MRK-13238, MGD-MRK-8850
References
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  • Summaries
    All 164
    Gene Ontology 4
    Phenotypes 62
  • Earliest
    J:5133 Lewis WH, et al., Electrophoretic heterogeneity of mouse erythrocyte peptidases. Biochem Genet. 1969 Oct;3(5):493-8
  • Latest
    J:257226 Jang Y, et al., Cutting Edge: Check Your Mice-A Point Mutation in the Ncr1 Locus Identified in CD45.1 Congenic Mice with Consequences in Mouse Susceptibility to Infection. J Immunol. 2018 Mar 15;200(6):1982-1987

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory