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Os Gene Detail
Summary
  • Symbol
    Os
  • Name
    oligosyndactylism
  • Synonyms
    94-A, 94-K, PlmTgN(Pgk1)1Ddp, PlmTgN(Pgk1)2Ddp
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97446
    NCBI Gene: 109678
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    39 experiments
Strain
Comparison
more
  • RFLP
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    34 phenotypes from 1 allele in 4 genetic backgrounds
    1 images
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mutations in this gene result in heterozygous mice with limb and kidney abnormalities. The homozygote dies soon after implantation.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 9
    cDNA 1
Other
Accession IDs
less
MGD-MRK-13054, MGI:892015, MGI:892016
References
more
  • Summaries
    All 60
    Phenotypes 31
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:282477 Baldelomar EJ, et al., In vivo measurements of kidney glomerular number and size in healthy and Os(/+) mice using MRI. Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F865-F873

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory