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Defa1 Gene Detail
Summary
  • Symbol
    Defa1
  • Name
    defensin, alpha 1
  • Synonyms
    cryptdin-1, Defcr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:94880
    NCBI Gene: 13216
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    16 experiments
Homology
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Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic AF178043 GenBank | EMBL | DDBJ | MGI Sequence Detail 617 129X1/SvJ ±  kb
transcript NM_010031 RefSeq | MGI Sequence Detail 427 Swiss albino  
polypeptide P11477 UniProt | EBI | MGI Sequence Detail 93 Not Applicable  
For the selected sequence
Polymorphisms
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  • RFLP
Protein
Information
less
Molecular
Reagents
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  • All nucleic 13
    Genomic 1
    cDNA 7
    Primer pair 3
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-8822
References
more
  • Summaries
    All 40
    Developmental Gene Expression 8
    Gene Ontology 5
  • Earliest
    J:10035 Ouellette AJ, et al., Localization of the cryptdin locus on mouse chromosome 8 [published erratum appears in Genomics 1992 Mar;12(3):626]. Genomics. 1989 Aug;5(2):233-9
  • Latest
    J:185753 van Es JH, et al., A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal. Mol Cell Biol. 2012 May;32(10):1918-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory