Dbf
Gene Detail

Symbol Name ID

Dbf doublefoot MGI:94863

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome 1
Syntenic

Mapping data(7)

Alleles and phenotypes

All alleles(1) : Spontaneous(1)
 

Homozygous mutants die late in emrbyonic development with split face, bulged heads and edema; heterozygotes have severe limb defects with duplicate toes on all feet, hindlimb shortening, broad skulls, clubbed feet, and reduced viability and fertility.

 
Human Diseases Modeled Using Mouse Dbf (1)    Alleles Annotated to Human Diseases(1)   

Other database links

Entrez Gene

109578

References

(Earliest) J:14233 Lyon MF, et al., Doublefoot, a new mutation affecting limb development. Mouse News Lett. 1989;83:158
(Latest) J:135300 Babbs C, et al., Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog. Mech Dev. 2008 May-Jun;125(5-6):517-26
All references(12)

Other accession IDs

MGD-MRK-8800