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Dbf
Gene Detail
 Symbol
Name
ID
Dbf
doublefoot
MGI:94863
Feature Type heritable phenotypic marker
Genetic Map
Chromosome 1
Syntenic

Mapping data(7)
Sequence Map
Chr1:59898872-82966353 bp
From MGI annotation of GRCm38

  23067482 bp   ±  kb flank

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Mouse Genome Browser
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Spontaneous(1)
 
Homozygous mutants die late in emrbyonic development with split face, bulged heads and edema; heterozygotes have severe limb defects with duplicate toes on all feet, hindlimb shortening, broad skulls, clubbed feet, and reduced viability and fertility.
 
Human Diseases Modeled Using Mouse Dbf (1)    Alleles Annotated to Human Diseases(1)   
Other database
links
Entrez Gene109578
References (Earliest) J:14233 Lyon MF, et al., Doublefoot, a new mutation affecting limb development. Mouse News Lett. 1989;83:158
(Latest) J:135300 Babbs C, et al., Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog. Mech Dev. 2008 May-Jun;125(5-6):517-26
All references(12)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-8800

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory