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Bmfr1 QTL Detail
Summary
  • Symbol
    Bmfr1
  • Name
    B cell maturation factor responsiveness 1
  • Synonyms
    Bmfr-1
  • Feature Type
    QTL
  • IDs
    MGI:88172
    NCBI Gene: 110636
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 4, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    4 experiments
Mutations,
Alleles, and
Phenotypes
less
This locus controls splenic B-cells ability to differentiate into antibody-secreting cells in response to B-cell maturation factors up to one month of age. Bmfr2 controls the response after one month of age. Strains differ in response alleles, but both loci show the same strain distribution pattern.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-1584, MGD-MRK-1586
References
more
  • Summaries
    All 5
  • Earliest
    J:8143 Sidman CL, et al., Two loci affecting B cell responses to B cell maturation factors. J Exp Med. 1986 Jan 1;163(1):116-28
  • Latest
    J:65671 Araujo LM, et al., NKT lymphocyte ontogeny and function are impaired in low antibody-producer Biozzi mice: gene mapping in the interval-specific congenic strains raised for immunomodulatory genes. Int Immunol. 2000 Nov;12(11):1613-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory