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anx Gene Detail
Summary
  • Symbol
    anx
  • Name
    anorexia
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88029
    NCBI Gene: 11743
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 2, Syntenic
  • Mapping Data
    4 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    25 phenotypes from 1 allele in 2 genetic backgrounds
    9 phenotypes from multigenic genotypes
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygotes for a spontaneous mutation exhibit reduced growth, head weaving, hyperactivity, low food intake, elevated serotonergic stimulation, altered neuropeptide Y processing in the hypothalamic arcuate nucleus, and periweaning lethality.
Sequences &
Gene Models
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References
more
  • Summaries
    All 24
    Phenotypes 21
  • Earliest
    J:28102 Williams CL, et al., Inhibition of suckling in weaning-age rats: a possible serotonergic mechanism. J Comp Physiol Psychol. 1979 Jun;93(3):414-29
  • Latest
    J:241666 Kim DY, et al., The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation. Dis Model Mech. 2017 May 01;10(5):581-595

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory