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Aem1 QTL Detail
Summary
  • Symbol
    Aem1
  • Name
    antierythrocyte autoantibody modifier 1
  • Synonyms
    Aem-1
  • Feature Type
    QTL
  • IDs
    MGI:87950
    NCBI Gene: 107710
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 4, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    3 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
This locus modifies the incidence of anti-erythrocyte autoantibodies (AEA) in crosses between NZB and C57BL/6 strains. The recessive allele in NZB allows 100% incidence of AEA and the dominant allele in C57BL/6 prevents production of AEA.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-1171, MGD-MRK-1172
References
more
  • Summaries
    All 3
    Phenotypes 1
  • Earliest
    J:7191 Ozaki S, et al., Genetic regulation of erythrocyte autoantibody production in New Zealand black mice. Immunogenetics. 1983;18(3):241-54
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory