Tg(ACTA1-Serpina3n)1Jmol
Transgene Detail

Summary

• Symbol: Tg(ACTA1-Serpina3n)1Jmol
• Name: transgene insertion 1, Jeffery Molkentin
• MGI ID: MGI:5708094
• Synonyms: Serpina3n TG
• Transgene: Tg(ACTA1-Serpina3n)1Jmol Location: unknown
• Alliance: Tg(ACTA1-Serpina3n)1Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA1-Serpina3n)1Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Serpina3n (MGI:105045)

• Mutation details: The transgenic construct contains mouse Serpina3n followed by a polyA tail under the control of a modified human ACTA1/SKA promoter. (J:228636)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:228636 Tjondrokoesoemo A, et al., Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice. Hum Mol Genet. 2016 Mar 15;25(6):1192-202
• All: 1 reference(s)