Rr34 Other Genome Feature Detail

Summary

• Symbol
  Rr34
• Name
  regulatory region 34
• Synonyms
  mm77

• Feature Type
  enhancer
  BioType Conflict
  
• IDs
  MGI:5616930
  NCBI Gene: 109279873

Location &
Maps

• Sequence Map
  Chr5:122230281-122232831 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic

Strain
Comparison

• SNPs within 2kb
  9 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for a knockout allele of this enhancer exhibit reduced Myl2 expression, reduced female mouse body weight, myocardial fiber disarray with karyomegaly and decreased cardiac muscle contractility.

Sequences &
Gene Models

• All Sequences
  3
• RefSeq
  1

• NCBI Gene
  109279873

Representative Sequences			Length	Strain/Species
genomic	109279873	NCBI Gene Model | MGI Sequence Detail	2551	C57BL/6J

Other Database
Links

VISTA Enhancer Element

mm77

References

• Summaries
  All 5

  Phenotypes 1
• Earliest
  J:252154 Dickel DE, et al., Genome-wide compendium and functional assessment of in vivo heart enhancers. Nat Commun. 2016 Oct 5;7:12923