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Rr27
Gene Detail
 Symbol
Name
ID
Rr27
regulatory region 27
MGI:5489785
Feature Type gene
Genetic Map
Chromosome 7
Syntenic
Alleles
and
phenotypes
All alleles(18) : Targeted(18)
 
Mice homozygous for one allele disrupting this imprinting control region (or differentially methylated region) between H19 and Igf2 exhibit normal methylation imprinting.
 
References (Earliest) J:28716 Leighton PA, et al., An enhancer deletion affects both H19 and Igf2 expression. Genes Dev. 1995 Sep 1;9(17):2079-89
(Latest) J:188518 Heaton JH, et al., Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and beta-catenin. Am J Pathol. 2012 Sep;181(3):1017-33
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory