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Rr27 Other Genome Feature Detail
Summary
  • Symbol
    Rr27
  • Name
    regulatory region 27
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:5489785
Location & Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 7, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 17 alleles in 12 genetic backgrounds
    32 phenotypes from multigenic genotypes
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    19
  • Targeted
    19
Mice homozygous for one allele disrupting this imprinting control region (or differentially methylated region) between H19 and Igf2 exhibit normal methylation imprinting.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
References
more
  • Summaries
    All 26
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:28716 Leighton PA, et al., An enhancer deletion affects both H19 and Igf2 expression. Genes Dev. 1995 Sep 1;9(17):2079-89
  • Latest
    J:222432 Susiarjo M, et al., Bisphenol a exposure disrupts metabolic health across multiple generations in the mouse. Endocrinology. 2015 Jun;156(6):2049-58

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory