Mirc35 Complex/Cluster/Region Detail

Summary

• Symbol
  Mirc35
• Name
  microRNA cluster 35, including Mir182 through Mir183
• Synonyms
  miR-183/96/182

• Feature Type
  complex/cluster/region
• IDs
  MGI:5475136
• Cluster Members
  Mir182, Mir96, Mir183 (3 members)

Location &
Maps

• Sequence Map
  Chr6:30165917-30169736 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, Syntenic

Strain
Comparison

• SNPs within 2kb
  57 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 2 genetic backgrounds
  5 phenotype references
  

• All Mutations and Alleles
  4
• Targeted
  4
• Find Mice (IMSR)
  4 strains or lines available

Mice homozygous for a conditional allele activated in neurons exhibit an increase in the proportion of Adelta low-threshold mechanoreceptors and decreased proportion of Abeta slowly adapting low-threshold mechanoreceptors and decreased mechanical nociceptive threshold.

Other Database
Links

miRBase

MI0000224, MI0000225

References

• Summaries
  All 11

  Phenotypes 5
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:327360 Wang Z, et al., Deletion of microRNA-183-96-182 Cluster in Lymphocytes Suppresses Anti-DsDNA Autoantibody Production and IgG Deposition in the Kidneys in C57BL/6-Fas(lpr/lpr) Mice. Front Genet. 2022;13:840060

Mirc35 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mir182, microRNA 182	miRNA gene	Chr6:30165917-30165991 (-)
Mir96, microRNA 96	miRNA gene	Chr6:30169445-30169550 (-)
Mir183, microRNA 183	miRNA gene	Chr6:30169667-30169736 (-)