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Del(13Simc1-B4galt7)2Dja Cytogenetic Marker Detail
Summary
  • Symbol
    Del(13Simc1-B4galt7)2Dja
  • Name
    deletion, Chr 13, David J Adams 2
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:5451180
Location & Maps
more
  • Genetic Map
    Chromosome 13, Syntenic
Human Diseases
more
  • Diseases
    1 with Del(13Simc1-B4galt7)2Dja mouse models

Human Disease Mouse Models
       Sotos Syndrome 1; SOTOS1   OMIM: 117550 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 4 genetic backgrounds
    1 images
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
Mice heterozygous for the deletion exhibit reduced fetal and postnatal growth with decreased lean body mass, impaired habituation to a novel odor and dilation of kidney calyx.
References
more
  • Summaries
    All 2
    Diseases 1
    Phenotypes 1
  • Earliest
    J:190741 Migdalska AM, et al., Generation of the Sotos syndrome deletion in mice. Mamm Genome. 2012 Dec;23(11-12):749-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory