About   Help   FAQ
Mirc32 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc32
  • Name
    microRNA cluster 32, including Mir143 and Mir145a
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5447365
  • Cluster Members
    Mir145a, Mir143 (2 members)
Location &
Maps
more
  • Sequence Map
    Chr18:61780896-61782329 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotypes from 6 alleles in 7 genetic backgrounds
    4 images
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit vascular smooth muscle hypotrophy, decreased blood pressure, decreased heart weight, and failure to respond normally to carotide artery ligation.
Other Database
Links
less
miRBase MI0000169, MI0000257
References
more
  • Summaries
    All 16
    Phenotypes 13
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:322146 Xu R, et al., Identification of the canonical and noncanonical role of miR-143/145 in estrogen-deficient bone loss. Theranostics. 2021;11(11):5491-5510

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
11/15/2022
MGI 6.22
The Jackson Laboratory