About   Help   FAQ
Mirc21 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc21
  • Name
    microRNA cluster 21, including Mir34c through Mir34b
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5313578
  • Cluster Members
    Mir34c, Mir34b (2 members)
Location &
Maps
more
  • Sequence Map
    Chr9:51014334-51014945 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 3 alleles in 3 genetic backgrounds
    34 phenotypes from multigenic genotypes
    4 images
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele of Mir34b and Mir34c exhibit increased reprogramming efficiency of mouse embryonic fibroblasts.
Other Database
Links
less
miRBase MI0000403, MI0000404
References
more
  • Summaries
    All 24
    Phenotypes 22
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:316889 Yuan S, et al., Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2102940118
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory