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Mirc20 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc20
  • Name
    microRNA cluster 20, including Mir302b through Mir367
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5313577
  • Cluster Members
    Mir302b, Mir302c, Mir302a ... (5 members)
Location &
Maps
more
  • Sequence Map
    Chr3:127545228-127545807 bp
  • From MGI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotypes from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a conditional allele activated in cardiac tissue exhibit normal programmed cell death and viability. Mice homozygous for a knock-out allele exhibit lethality during fetal development, incomplete rostral neuropore closure, exencephaly and precocious neuronal development.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Other Database
Links
References
more
  • Summaries
    All 8
    Developmental Gene Expression 1
    Phenotypes 6
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:262025 Pi J, et al., A MicroRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability. Circ Res. 2017 Jan 6;120(1):85-98

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory