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b2b464Clo Gene Detail
Summary
  • Symbol
    b2b464Clo
  • Name
    Mutant line 464
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:5311027
  • Alliance
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome Unknown
Human Diseases
more
  • Diseases
    1 with b2b464Clo mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    10 images
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygotes exhibit hypoplastic left ventricle (LV), aortic valve hypoplasia, hypoplastic aorta (Ao), hypoplastic mitral valve, aortic arch hypoplasia and atrial septal defect (ASD).
References
more
  • Summaries
    All 3
    Diseases 1
    Phenotypes 3
  • Earliest
    J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4
  • Latest
    J:242757 Liu X, et al., The complex genetics of hypoplastic left heart syndrome. Nat Genet. 2017 Jul;49(7):1152-1159

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory