Mirc4 Complex/Cluster/Region Detail

Summary

• Symbol
  Mirc4
• Name
  microRNA cluster 4, including Mir429 through Mir200b

• Feature Type
  complex/cluster/region
• IDs
  MGI:5049941
• Cluster Members
  Mir429, Mir200a, Mir200b (3 members)

Location &
Maps

• Sequence Map
  Chr4:156138362-156140207 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, Syntenic

Strain
Comparison

• SNPs within 2kb
  74 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from multigenic genotypes
  4 phenotype references
  

• All Mutations and Alleles
  3
• Targeted
  3
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for a conditional allele activated in teh pancreas exhibit partial protection from streptozotocin-induced diabetes.

Other Database
Links

miRBase

MI0000243, MI0000554, MI0001642

References

• Summaries
  All 6

  Phenotypes 4
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:267194 Title AC, et al., Genetic dissection of the miR-200-Zeb1 axis reveals its importance in tumor differentiation and invasion. Nat Commun. 2018 Nov 7;9(1):4671

Mirc4 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mir429, microRNA 429	miRNA gene	Chr4:156138362-156138444 (-)
Mir200a, microRNA 200a	miRNA gene	Chr4:156139353-156139442 (-)
Mir200b, microRNA 200b	miRNA gene	Chr4:156140138-156140207 (-)