About   Help   FAQ
Rr7 Other Genome Feature Detail
Summary
  • Symbol
    Rr7
  • Name
    regulatory region 7
  • Synonyms
    CD8/LCR
  • Feature Type
    locus control region
  • IDs
    MGI:4837099
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 6, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 5 alleles in 4 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted mutation exhibit disregulation of Cd8a and Cd8b expression.
References
more
  • Summaries
    All 3
    Phenotypes 2
  • Earliest
    J:164573 Menzel U, et al., Replication allows inactivation of a knocked-in locus control region in inappropriate cell lineages. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16928-33
  • Latest
    J:179326 Menzel U, et al., Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences. J Immunol. 2011 Oct 1;187(7):3712-20
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory