Tg(KRT5-ATF3)1Mcld
Transgene Detail
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Symbol: |
Tg(KRT5-ATF3)1Mcld |
Name: |
transgene insertion 1, Michael C MacLeod |
MGI ID: |
MGI:4452619 |
Synonyms: |
BK5.ATF3 |
Transgene: |
Tg(KRT5-ATF3)1Mcld Location: unknown
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Alliance: |
Tg(KRT5-ATF3)1Mcld page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(KRT5-ATF3)1Mcld expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
ATF3 (467) |
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Tg(KRT5-ATF3)1Mcld expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
cattle |
KRT5 (281268) |
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Mutation details: This transgene contains the bovine keratin 5 promoter driving expression of a full length cDNA representing the long transcript of human activating transcription factor 3 (ATF3). Strong expression of the human protein was observed in the nuclei of basal cells of the epidermis, hair follicles and oral mucosa.
(J:121782)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:121782 Wang A, et al., Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells. Mol Carcinog. 2007 Jun;46(6):476-87 |
All: |
3 reference(s) |
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