Tg(H2-Ea-Cd74/MCC)37GNnak
Transgene Detail

Summary

• Symbol: Tg(H2-Ea-Cd74/MCC)37GNnak
• Name: transgene insertion 37G, Naoko Nakano
• MGI ID: MGI:4439128
• Synonyms: Ii-MCC
• Transgene: Tg(H2-Ea-Cd74/MCC)37GNnak Location: unknown
• Alliance: Tg(H2-Ea-Cd74/MCC)37GNnak page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-Ea-Cd74/MCC)37GNnak expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cd74 (MGI:96534)

• Mutation details: The H2-Ea promoter was used to control expression of a fusion protein composed of Cd74 (MHC II invarient chain) and sequence encoding amino acid residues 88-103 of moth cytochrome c. (J:133061)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:133061 Yamashiro H, et al., Development of CD25(+) T cells secreting transforming growth factor-beta1 by altered peptide ligands expressed as self-antigens. Int Immunol. 2002 Aug;14(8):857-65
• All: 4 reference(s)