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Tg(Lck-Akt2)1Test
Transgene Detail
Summary
Symbol: Tg(Lck-Akt2)1Test
Name: transgene insertion 1, Joseph R Testa
MGI ID: MGI:4397666
Transgene: Tg(Lck-Akt2)1Test  Location: unknown  
Alliance: Tg(Lck-Akt2)1Test page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Lck-Akt2)1Test expresses 1 gene
 
Mutation detailsA cDNA for mouse Akt2 carrying a myristylation signal and using a human growth hormone polyadenylation signal was placed under the control of the Lck promoter. Five founder lines were produced. Integration sites for three of these lines are on Chromosomes 3, 7, and 10. The integration site is not specified for this transgene. (J:132762, J:154583)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:132762 Tan Y, et al., A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. Cancer Res. 2008 Mar 1;68(5):1296-302
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory