Tg(KRT5-Akt1*)L60Jmpa
Transgene Detail
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Symbol: |
Tg(KRT5-Akt1*)L60Jmpa |
Name: |
transgene insertion L60, Jesus M Paramio |
MGI ID: |
MGI:3842826 |
Synonyms: |
BK5.myrAktL60 |
Transgene: |
Tg(KRT5-Akt1*)L60Jmpa Location: unknown
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Alliance: |
Tg(KRT5-Akt1*)L60Jmpa page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(KRT5-Akt1*)L60Jmpa expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Akt1 (MGI:87986) |
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Tg(KRT5-Akt1*)L60Jmpa expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
cattle |
KRT5 (281268) |
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Mutation details: The bovine promoter was used to drive epithelial-specific expression of a myristoylated mouse Akt1. Two lines were created (L60 and L84).
(J:127302)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:127302 Segrelles C, et al., Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis. Cancer Res. 2007 Nov 15;67(22):10879-88 |
All: |
2 reference(s) |
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