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Bxs6 QTL Detail
Summary
  • Symbol
    Bxs6
  • Name
    BXSB/MpJ autoimmune nephritis 6
  • Feature Type
    QTL
  • IDs
    MGI:3836287
Location &
Maps
more
  • Sequence Map
    Chr13:45210442-83744746 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    2 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    6 phenotypes from multigenic genotypes
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
References
more
  • Summaries
    All 3
    Phenotypes 3
  • Earliest
    J:145903 Haywood ME, et al., Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice. J Immunol. 2001 Aug 1;167(3):1728-33
  • Latest
    J:149277 Yoshinobu K, et al., Selective up-regulation of intact, but not defective env RNAs of endogenous modified polytropic retrovirus by the Sgp3 locus of lupus-prone mice. J Immunol. 2009 Jun 15;182(12):8094-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory