Bxs6 QTL Detail

Summary

• Symbol
  Bxs6
• Name
  BXSB/MpJ autoimmune nephritis 6

• Feature Type
  QTL
• IDs
  MGI:3836287

Location &
Maps

• Sequence Map
  Chr13:45210442-83744746 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from 1 allele in 2 genetic backgrounds
  6 phenotypes from multigenic genotypes
  3 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 3
• Earliest
  J:145903 Haywood ME, et al., Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice. J Immunol. 2001 Aug 1;167(3):1728-33
• Latest
  J:149277 Yoshinobu K, et al., Selective up-regulation of intact, but not defective env RNAs of endogenous modified polytropic retrovirus by the Sgp3 locus of lupus-prone mice. J Immunol. 2009 Jun 15;182(12):8094-103