Tg(Fgfr3-icre/ERT2)4-2Wdr
Transgene Detail

Summary

• Symbol: Tg(Fgfr3-icre/ERT2)4-2Wdr
• Name: transgene insertion 4-2, William D Richardson
• MGI ID: MGI:3832576
• Synonyms: Fgfr3-icreER^T2, Tg(Fgfr3-icre/ERT2)1Wdr
• Transgene: Tg(Fgfr3-icre/ERT2)4-2Wdr Location: unknown
• Alliance: Tg(Fgfr3-icre/ERT2)4-2Wdr page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Fgfr3-icre/ERT2)4-2Wdr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fgfr3 (MGI:95524)

• Mutation details: A mouse PAC clone (RPCI21-608P12) containing the Fgfr3 gene was modified by the insertion of icreERT2 and an SV40polyA sequence into exon 2 (the first coding exon). (J:144591)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fgfr3 (mouse) Summary of all recombinase alleles driven by Fgfr3. Comparative matrix view of recombinase activities Alliance mouse Fgfr3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:144591 Rivers LE, et al., PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci. 2008 Dec;11(12):1392-401
• All: 31 reference(s)