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In(10)17Rk Cytogenetic Marker Detail
Summary
  • Symbol
    In(10)17Rk
  • Name
    inversion, Chr 10, Roderick 17
  • Synonyms
    Hmga2pg-J, In17Rk, pygmy Jackson
  • Feature Type
    chromosomal inversion
  • IDs
    MGI:3790438
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 10, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for this inversion are small and sterile. The phenotype is similar to the pygmy mutation and is attributable to the location of the distal inversion breakpoint in the Hmga2 gene.
References
more
  • Summaries
    All 6
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:74548 Benson KF, et al., Molecular Characterization of the Mouse In(10)17Rk Inversion and Identification of a Novel Muscle-Specific Gene at the Proximal Breakpoint. Genetics. 2002 Jan;160(1):279-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory