Del(2Hoxd11-Hoxd13)29Ddu Cytogenetic Marker Detail

Summary

• Symbol
  Del(2Hoxd11-Hoxd13)29Ddu
• Name
  deletion, Chr 2, Denis Duboule 29
• Synonyms
  Del, Del29Ddu, HoxD^d11lacZDel3, HoxD^Del, Hoxd^tm2Ddu

• Feature Type
  chromosomal deletion
• IDs
  MGI:3762254

Location &
Maps

• Sequence Map
  Chr2:74498654-74517360 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotypes from 1 allele in 1 genetic background
  15 phenotypes from multigenic genotypes
  22 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  2 strains or lines available

References

• Summaries
  All 24

  Phenotypes 22
• Earliest
  J:33879 van der Hoeven F, et al., Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls. Cell. 1996 Jun 28;85(7):1025-35
• Latest
  J:283343 Bastida MF, et al., The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096