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sevr Gene Detail
Summary
  • Symbol
    sevr
  • Name
    severe runting
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3624557
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:61272448-63875042 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    2 images
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygotes for this spontaneous mutation are severely runted, exhibit tremors, thymus atrophy, and postnatal and premature death.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:109437 Harris B, et al., Severe Runting (sevr): A New Mouse Mutation on Mouse Chromosome 18. MGI Direct Data Submission. 2006;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory