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Nstr1 QTL Detail
Summary
  • Symbol
    Nstr1
  • Name
    nerve sheath tumor resistance QTL 1
  • Feature Type
    QTL
  • IDs
    MGI:3524871
    NCBI Gene: 100035039
Location &
Maps
more
  • Sequence Map
    Chr19:5321112-5321310 bp
  • From MGI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.30 cM (cM position of peak correlated region/marker)
  • Mapping Data
    2 experiments
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    1 phenotype reference
Mice homozygous for a null allele exhibit decreased antinociception, body temperature reduction, impaired coordination and hypoperistalsis in response to neurotensin 2.
Sequences &
Gene Models
less
References
more
  • Summaries
    All 3
    Phenotypes 1
  • Earliest
    J:105038 Reilly KM, et al., An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model. Cancer Res. 2006 Jan 1;66(1):62-8
  • Latest
    J:147432 Walrath JC, et al., Chr 19(A/J) modifies tumor resistance in a sex- and parent-of-origin-specific manner. Mamm Genome. 2009 Apr;20(4):214-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory